L-Tyrosine

Specifications of L-Tyrosine

Chemical Name: 2-amino-3-(4-hydroxyphenyl)propanoic acid.

Molecular Formula: C9H11NO3

Molecular Weight:181.19 g/mol

CAS Number: 60-18-4

L-Tyrosine is a non-essential amino acid used by cells for protein synthesis. It is synthesized in the body from the essential amino acid phenylalanine. L-Tyrosine has a polar side chain with a phenolic group, making it both hydrophilic and hydrophobic in character. It plays important roles beyond protein building—serving as a precursor for critical neurotransmitters such as dopamine, norepinephrine, and epinephrine. It is also involved in the production of thyroid hormones (thyroxine), the pigment melanin, and coenzyme Q10.

Appearance: White crystalline powder or white to pale brown solid, odorless

Solubility: Slightly soluble in water (~0.45 g/L at 25 °C), soluble in dilute acids and bases, insoluble in ethanol, ether, benzene

Melting Point: 290 °C 

L-Tyrosine nutritional information typically includes:

  • It is a non-essential amino acid, meaning the body can synthesize it from phenylalanine.

  • Commonly available as a supplement in doses of around 500 mg per capsule.

  • It is sourced from high-protein foods such as cheese, chicken, fish, and soy.

  • In supplements, each typical serving (e.g., one capsule) provides 500 mg of L-Tyrosine.

  • Being an amino acid, it contributes protein but contains no fat or carbohydrates.

  • There is no specific caloric value typically assigned to single amino acids like L-Tyrosine in isolation, but as a protein component, it provides about 4 kcal per gram if fully metabolized.

  • Daily intake recommendations can vary but often fall within 1 to 4 capsules (500–2000 mg total) depending on use.

  • Used to support neurotransmitter production and various physiological functions linked to protein metabolism.

L-Tyrosine benefits mainly arise from its role as a precursor to important neurotransmitters and hormones, and its involvement in protein synthesis. Key benefits include:

  • Improved Mental Sharpness and Cognitive Function: L-Tyrosine supports brain function, especially under stress. It may help maintain working memory, attention, and task performance during mentally demanding or stressful situations, including sleep deprivation and physical stress.

  • Mood Regulation and Potential Anti-Depressant Effects: As a precursor to dopamine, norepinephrine, and epinephrine, L-tyrosine influences mood and motivation. Some research suggests it may help improve mood and alleviate symptoms of depression, although findings are mixed.

  • Support for Stress Response: By replenishing depleted catecholamines (dopamine, norepinephrine) during stress, L-tyrosine may enhance the ability to manage mental, emotional, and physical stress.

  • Production of Thyroid Hormones: L-tyrosine is vital for synthesizing thyroid hormones that regulate metabolism, impacting energy balance and overall health.

  • Melanin Production: It contributes to the production of melanin, influencing skin, hair, and eye pigmentation, and offering some protection against sun damage.

  • Potential Physical Performance Benefits: Preliminary evidence suggests L-tyrosine may improve physical endurance and performance under certain conditions, but more research is needed.

  • Therapeutic Use in Phenylketonuria (PKU): Since PKU impairs phenylalanine metabolism (which is a precursor of tyrosine), supplementation can help maintain normal tyrosine levels and support associated metabolic functions.

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